Big Things: Giants and Dragons
Giant Races
Jotunkin (tweak the already-posted Giantkin), and also throw in stuff for other giants: Orogs and/or Ettins (maybe make Orogs the general brutish type and Two Heads a feat) and Trolls. Include Paragon Classes for each one, and maybe prestige classes for specific giant types. Giants probably don't need a Giant class; they can take levels in Barbarian or whatever instead.
Dragons
General rant about Dragons
Dragon Race
Write up traits for a Dragon race here.
Dragon Classes
Draconic Sage (Spherecaster), Drake (Brute), True Dragon (True Dragon)
Metallic Paragon and Chromatic Paragon (Prestige classes)
Maybe some other Prestige Classes
Example Dragons
Megabeasts
Megabeasts are single organisms that are treated game mechanically as several creatures fused together. For example, a Great Dragon's head, wings, body, and tail each count as a separate creature. They use these rules and are entirely unsuitable for use as player characters.
Great Dragons (template to make them with dragon classes)
Zaratan (Head, 2 Forelimbs, 2 Hindlimbs, Tail)
Maybe a fiend of some kind
Other stuff (Treant?)
Colossoecology
General rant about how big things fit into ecosystems
Lairing
General rant about the lairs of big things
Maybe have some stuff to put in their lairs, too.